Thursday, January 23, 2014

Justin Bieber Arrest News

Justin Bieber was charged for drag racing in florida.

Actor Seth Rogen commented on Twitter: All jokes aside, Justin Bieber is a piece of s***.'



Scamperghost And Pac-Avoid: Diffrent name but the same game !

Scamperghost game is the product of Junkyard Sam & Nick Bray a.k.a Stolen Goose where as Pac-Avoid is made by king.com.
According to source king.com quickly build the direct clone of Scamperghost named as Pac-Avoid.

See the images below ...

Game Menu 


Gameboard & User Interface





Game Over 

Saturday, September 21, 2013

LinkedIn Sued By Their Customers

The world's very well known professional website has received sue notice by their own customers for hacking their credentials and using them for marketing purpose.

According to their customer LinkedIn hacked their external email accounts and download their contact addresses.

Even customers are planning to take a stand for leading a group against LinkedIn.    

Due to this LinkedIn have to face the 2.1% downfall in New York stock Exchange.

The speaker of LinkedIn says the company will fight against it because the lawsuit has no merit.

see full story here. 

Tuesday, July 23, 2013

Porn Paused By Default In UK



Internet is available with Enable\Disable Porn Option. Which is Disable by default.

If you want to see porn in UK you have to enable this service via Internet Provider.

David Cameron Says: "In the balance between freedom and responsibility we have neglected our responsibility to children"

A new measurement to be applied in new and existing internet customers in UK.

Also appealed for blocking of "Those" Internet search terms in major Search Engines like Google, Bing & yahoo.

Customers who do not click on either option - accepting or declining - will have filters activated by default.

"rape porn" banned There.

Online viewing of Child Sex video and Images became serious crime in UK

Friday, May 17, 2013

Internet Porn: Truth in Figures

A Porn site revealed its Traffic data : 


  • 100 million

    page views per day 
  • At peak hours

    4000 page views

    per second
  • Streaming nearly

    100 gigabytes

     
  • 65 million

    unique visitor a day

Reddit

Receives

13 million

unique visitors per month

Facebook

gets

600 to 700 million visitors


According to

Google

popular video sites receives :
  • 4.46 billion page views per month

  • 350 million unique visitor monthly

porn video websites also receives visitors from

"Vatican city" 

Tuesday, February 26, 2013

Oscar 2013 pictures

producer Grant Heslov and Ben Affleck in Oscar


Channing Tatum and actress Charlize Theron perform a dance in Oscar 2013


Actress Jennifer Lawrence won the best Oscar actress award 2013 

Reese Witherspoon in oscar














Barbra Streisand in oscar














Adele in oscar













Ang Lee as the best director for the movie life of pi













Shirley Bassey performs goldfinger in oscar













Andrea Nix Fine and Sean Fine in oscar













Best Oscar original screenplay for Django









Quentin Tarantino

Sunday, February 17, 2013

Let's Think !!



Have you ever stuck in that situation? It’s like god is treating you like a fool. I am also the man of simple pleasure. But nowadays simple pleasure is something becomes very rare to find. Sometimes it is much precious than diamond.

Loneliness is the killing one. 

Q.Girls don't feel too bad if the boys are having more than one relationship... but when it comes to boys...they can not accept it... actually they can not even listen it? 

Wednesday, November 14, 2012

Ever you thinking What is Cannabis !

What is cannabis?
---------------
What is Cannabis. Cannabis, the worlds most popular drug is just a herb. A particular processing of the cannabis herb creates marijuana, a medicine, and a recreational drug. Cannabis has been consumed by humans since the Third Millenium BCE. It has been found with mummies buried 2500-2800 years ago in China and Egypt. It has also been found to be consumed in ancient India and Nepal. In modern history, it was used in the 1940s as "truth serum". 

Many famous celebrities have been known to smoke weed. Justin Timberlake, Micheal Phelps, Snoop Dogg, Li'l Wayne and the most well-knowncannabis consuming personality of all times, Bob Marley. Also, traces from shakespeare's pipe indicates he took weed.

Using Marijuana
----------------
Marijuana is normally smoked in rolled ciggarates known as joints. It is also taken by using pipes. Marijuana can also be smoked by using water-pipes popularly known as bongs. It can also be brewed in tea, or mixed with brownies or cookies. When rolled in a cigar wrapper, it's called a blunt. 

Thursday, September 20, 2012

iOS 6 Release Date and Information Before you Download It


Apple's iOS 6 is now introduced.. download it. you can also upgrade to iOS 6 in a very short period of time (few hrs.)- the iOS 6 release time should be around 10 a.m. PST/ 1 p.m. EST.


For anyone with an iPhone 3GS and up, the iPad 2, iPad 3, and the fourth-generation iPod touch, the chargeless download of iOS 6 is a far bigger advancement than bottomward a few hundred dollars on Apple's new iPhone 5.

iPhone 5 reviews are just hitting the web, and they are calmly the a lot of aglow adaptable buzz reviews in history. Sure, the faster processor, absurd iSight camera, and beyond awning are big hits, but iOS 6 is just as big a brilliant in its own right.

If you are advance to iOS 6 today, we accept included all of the tips and tricks that you charge to apperceive to upgrade, as able-bodied as a account of some of the best new things iOS 6 has to offer.
Here is aggregate you charge to apperceive advanced of the iOS 6 absolution time.

iOS 6 Release Date

iOS 6 was appear endure anniversary and the iOS 6 absolution date is now today. We should apprehend to see it attainable for download about 10am PST/ 1pm EST. You will be able to download iOS 6 on Wednesday September 19th. Apple appear iOS 6 at Apple's Chat Wide Developers conference, however, it has alone been attainable for developers aback then. iOS 6 will be accurate on the iPhone 4S, iPhone 4, iPhone 3GS, iPad 2, new iPad and fourth gen iPod touch.

Over the Air Update

This is the aboriginal time that you will be able to advancement operating systems after active in your buzz to your computer. If you are currently active iOS 5 you will be able to advancement to iOS 6 over the air.

iTunes 10.7

You will charge iTunes 10.7 afore you advancement to iOS 6. Download it now!

Must keep your Back Up

Upgrading operating systems consistently runs the accident of abstracts loss. Accomplish abiding you aback up all of your abstracts afore hand.

Charge Phone

Make abiding your buzz is answerable or a ability bond is nearby. Active out of array during an advancement could spell disaster.

About iOS 6

YouTube and Google Maps is Not Available
As the action amid Apple and Google heats up, Apple has alone the preloaded YouTube and Google Maps applications. Not abundant chat yet on the superior of the apps Apple has implemented on its buzz instead. We'll just accept to delay and analysis for ourselves. If Apple's new Maps affection can at atomic amount out which administration is "left" blush us impressed.

Major Siri's upgrade
You can now get sports bold updates, accomplish restaurant anxiety on OpenTable, watch cine trailers and added on Rotten Tomatoes, barrage apps, and even cheep by voice. Siri is now aswell attainable for the iPad.

App Store
According to a address today, the App abundance is accepting a one blow download for chargeless apps. Fantastic account for anybody ailing of the three clicks it currently takes.

Facebook Integration
Facebook will accommodate with iOS 6 in a agnate way Twitter currently integrates with iOS 5.

New Buzz App Features
You can now set reminders to alarm humans back, forward letters instead of calling, administer a "DO NOT DISTURB" affection that does not active you with notifications.

iCloud Tabs
iCloud Tabs will accommodate Safari beyond all iCloud-connected devices, acceptance users to go from accessory to accessory with the aforementioned internet browsing tabs actual attainable on each.

Mail VIPs
iOS 6 Mail VIPs will accredit to users to mark assertive contacts as important, and in turn, all their letters will be starred.

FaceTime over 3G
Once aloof for Wi-Fi only, you can now FaceTime over your cellular network.

Photo Stream
Photo Stream will acquiesce you to calmly allotment photos in real-time with your friends. Sounds accustomed to us ... ahem Samsung Galaxy S 3 cough.

Maps
Apple has coiled goodbye to Google Maps and reveled a new Maps app fabricated absolutely in-house. 3-D maps, aesthetically adorable functionality, and voice-prompted turn-by-turn aeronautics are area Apple's new app shines brightest. Although, users assume disconnected on whether or not this is an advance over Google Maps.

Guided Access
Guided Access allows you to lock an app if it's in use so that added controls will not be accessible.

Passbook
We've already discussed the abundant abeyant of Apple's new Passbook app, and there's a lot to get aflame about here. The app is one of alone a few technologies assertive to accompany us the next big tech addition crown: authoritative your buzz a agenda wallet.

Passbook is an app that will put all your agenda coupons, tickets and adherence cards in one place, and potentially, be a way one day to use the iPhone as a agenda wallet. There has been abundant allocution in the accomplished few years about axis phones into agenda wallets -- absolution humans use their phones to cream the Internet, accomplish calls and pay for lattes and muffins.

"Every befalling I accept to get in foreground of a client, it's the aboriginal affair I allocution about," says David Reeves, carnality admiral of the 22squared commercial agency. "This is huge. Apple doesn't do annihilation halfway. This is a amazing befalling to accommodate the way we use our wallets."
The iPhone 5 is allotment Passbook over NFC, partly because abounding analysts, like Shaw Wu, an analyst at Sterne Agee, altercate the technology just isn't there yet, and that the dent hogs too abundant array power.

But Wu does apprehend Passbook to pave the way for adaptable payments eventually. Apple just has to get a analytical accumulation of consumers application it. At that point, Apple will be able to actuate retailers to improve their transaction accessories to plan with the iPhone.

Visa, MasterCard, Starbucks, Google, Square, PayPal, Intuit and others accept been alive feverishly to accomplish adaptable payments a way of life, but the convenance has yet bolt on in the mainstream, because businesses are cat-and-mouse for it to become added widespread.

"With Passbook, you can browse your iPhone or iPod Blow to analysis in for a flight, get into a cine and redeem a coupon," Apple says on its website. "You can aswell see if your coupons expire, area your concert seats are, and the antithesis larboard on that all-important coffee bar card."

"Your adaptable accessory will become your wallet. Whether it's in a few months, a year from now or longer, it's traveling to happen," Daniel Delshad developer of a new app, Loyaldash, says.
According to Wu, the all-embracing bold plan for Apple is to accept the smartphone do aggregate -- alpha the car, lock it, attainable the abode and garage, about-face on the air conditioner and boiler -- and, of course, become the car to pay for appurtenances with a abrupt bash of the phone.





Tuesday, September 18, 2012

Kate Middleton Topless Photos Bound for Italy

An Italian account annual will broadcast the acclaimed Kate Middleton topless photos ... added anarchic the Royals.


Chi, endemic by the aforementioned aggregation that publishes French mag Closer (the aboriginal to broadcast the pics), will run a 26-page advance Monday. The banderole -- "The Queen is Nude."
Editor Alfonso Signorni says he doesn't abhorrence acknowledged activity -- Closer has already been sued -- because the photos are now allotment of accessible domain, adding, "I don't see annihilation aberrant or damaging in them. Chi pays absorption to apropos people's dignity. I don't anticipate they aching Kate's image."


Prince William's appointment is belief "all adapted responses" to Chi's affairs to broadcast the pics.

Wednesday, September 5, 2012

Something Interesting About Nazanin Boniadi



Before the globe saw Tom Cruise jumping on Oprah's couch for Katie Holmes, a conceit honest cowl story claims that the Church of faith auditioned girls to probably become his romantic partner. (Reps for the actor and faith have denied these claims.)

The magazine reports that 32-year-old Nazanin Boniadi was the highest selection as Tom's girlfriend (and potential wife) in 2004.

So WHO is she? Here square measure 5 belongings you got to realize Nazanin Boniadi

She's a world Lady: Per her official web site, Nazanin was "born in Iranian capital at the peak of the Iranian revolution." Her folks settled to London whereas she was young, and she or he later moved to the U.S. for faculty. She is "fluent in each English and Farsi," per her web site, and she's a political candidate spokesperson for Amnesty International USA.

She's very Smart: Despite some expertise as a baby actor, Nazanin determined she needed to become a Dr., per her web site. The brunette beauty attended the University of American state Irvine wherever she received her degree with Honors and won a present for her add heart-transplant rejection and cancer analysis. Bravo!

She's Been a Soap Star. Nazanin's initial major role was on General Hospital. From 2007 to 2009, she vie Leyla Mir, a nurse with aspirations of changing into a doctor.

She's Been Romanced by Barney Stinson: WHO desires Tom after you will have Barney?! Nazanin vie Neil patron saint Harris' love interest on however I Met Your Mother for 9 episodes in 2011.

She Costarred with martyr Clooney: Fine, it absolutely was during a Nespresso business (see above!). Still, not too many women have the honour of swapping suitcases or sharing the screen with America's favorite red fox.

Clearly, Nazanin's doing simply fine while not a hoop from Tom.

Tuesday, August 7, 2012

August 2012 price for Disney

Prices begin the month at the values 55% higher than the lowest of the year, and moderate prices are 20% higher. On August 5 these prices drop to 3-5% higher than the lowest of the year.

Deluxe prices begin the month 3% higher than the lowest of the year, and on 8/19 drop to their lowest level of the year.

Click the image to see a Pop Century Resort example of Disney World resort pricing.

Monday, March 26, 2012

world Famous singers cum rappers how looks in childhood !!

Usher Raymond IV


Usher has won grammy awards 5 times. At a very little age he can generate music and started performing in church coir and talent shows. Usher motivated by highland park boys club due to which he can fulfill his dream in music world. User founded a non-profil organisation called usher new look in the year 1999. With the help of this organisation youth can get the knowledge of business of sports as well as entertainment.











Jennifer Lopez


The girl started to showing her talent from Kips Bay Boys and Girls Club which is located in the bronx at New York City. Her first feature film debut introduced in the year 1995. In 1997 she won Best Actress award from Latino Media Arts. She is the faim of entertainment world she amazingly perform singing, dancing and Acting.











Ne-Yo


As a child growing up in the inner-city of Las Vegas, Shaffer Smith -- also known as singer/songwriter/entertainer Ne-Yo -- and his sister Nicole took refuge in Boys & Girls Clubs in Henderson and Las Vegas, Nev. His mom, Loraine, recognized that while young Shaffer was talented, he was also bored and needed an outlet. She turned to her nearby Club.
Now a successful recording artist, Ne-Yo remembers his roots by giving back to the organization which gave him and his family security and fun. In December 2009, Ne-Yo’s nonprofit foundation hosted its 3rd Annual Giving Tour at the Lied Memorial Boys & Girls Club, with the Grammy-Award winner personally delivering MP3 players, bicycles, toys, and big hugs, to more than 500 deserving youth at the Club.






Saturday, March 24, 2012

Don't ask for job applicant's password otherwise I’ll sue you : Facebook


Finally facebook has taken a action against the emaployers who are asking for username and password of employees and job applicants. According to report interviewers are demanding for id and password of applicants. Although it is not a new thing that employers are tracking the applicants and employees activity on social media websites but tracking their information from social websites which they have shared publicly is restricted. Facebook also replies that they can look for change in policy or lawsuits to secure emloyers from asking password.

Facebook takes stands on behalf of its users make them more secure. No doubt facebook is too serious from the user’s privacy side. They take action to make users more secure by engaging policy issues and legal action which also includes shutting down apps that breach their privilages. This satement is said by chief privacy officer of facebook Erin Egan. 

Although, sharing and making the facbook’s user password sociazing is already a violation term which was already mention in facebook’s user agreement.  To get a job one must not share their privacy and communication said by facebook. They also insured that every user of facebook need nothing to worry from privacy side. Your privacy was not going to revelaed in front of those who don’t know you. Due to demanding of password for job, facebook has added a statement of right and responsibilities for sharing.  It helps in prevention of socilizing of facebook’s password. 

Member  or employer from protected group on facebook must hire another employer if they don’t do so then that employer can claim for discrimination.  

Right now there is no employers on the list to take legal action. They are working on making a good protection strategy of their user’s privacy replied by facebook.

Wednesday, March 21, 2012

NJ Man Must Share Mega Millions Jackpot With Co-Workers


Money comes, money goes — especially for the defendant in the New Jersey Mega Millions lawsuit. A jury has awarded $20 million to the former co-workers of Americo Lopes, leaving him with only a sixth of his original $38.5 million ($24 million after taxes) lottery jackpot.

The co-workers sued Lopes after he refused to share the winnings. They claimed he used money from a group lottery pool to buy the 2009 winning ticket. Lopes disagreed, and instead argued that he had bought the ticket for himself.

Before the six co-workers struck gold, the group had been pitching in and buying weekly lottery tickets for at least three years. Each put $2 into the pool, and Americo Lopes would return with 12 lines of tickets, explains the New York Post.

Lopes claims that, during the winning week, he also bought 12 lines of tickets for himself, reports MSNBC. The winning numbers were on a ticket he allegedly purchased with his own money.
The jury obviously didn’t buy this argument. Lopes’ attorney brought in more than 1,000 of his previously purchased lotto tickets, reports the New York Post. He was trying to show that the winning ticket mirrored a pattern in Lopes’ past personal bets. But not one of Lopes’ personal tickets was worth $12.

This little tidbit is what likely won the Mega Millions lawsuit for the plaintiffs. It showed that Americo Lopes only ever bought 12 rows of tickets when playing for the group. It was out of the ordinary for him to play that many rows for himself.

Now, don’t think this is the end of the Mega Millions lawsuit. Lopes can still appeal the award. And given his anger at the verdict, it appears that he just might.


Source :- http://www.reuters.com/article/2012/03/20/tagblogsfindlawcom2012-decided-idUS282926040120120320

Monday, March 19, 2012

Frozen Planet - Are you aware of earth's "Nature"

NEW YORK -- "The best stories on our planet are natural ones," Alastair Fothergill says.


But you'd expect him to say that. For two decades with the BBC, Fothergill has produced wildlife documentary series including "Planet Earth," "Blue Planet" and, back in 1993, "Life in the Freezer," which explored Antarctica in all its frigid wonder.

Now he's executive producer of "Frozen Planet," a Discovery Channel/BBC co-production that takes a fresh look at Antarctica as well as its north-end counterpart, the Arctic, in seven gorgeous episodes premiering with the first two hours at 8 p.m. today on Discovery. And although you may not be ready to dismiss filmdom's stars and screenplay writers as unnecessary, "Frozen Planet" makes a strong case that Nature -- captured in the wild -- can equal Hollywood for epic sweep and drama.

Comedy, too. In Sunday's second hour, male penguins by the hundreds of thousands anticipate the spring return of the females, for whose favor each male must compete by building a swankier nest than his rivals. In a delightful sequence, a painstaking penguin gathers stones one by one, only to have them filched, one after another, by a scheming neighbor whenever the hapless suitor's back is turned. These performers, with their Chaplin-esque gait and impeccable timing, would have been right at home in a 1920s two-reeler.

There's also bittersweet romance on "Frozen Planet." Nature's ultimate loner, a 1,400-pound male polar bear, has lumbered across the ice all winter in search of a mate come spring. Picking up her scent from 10 miles away, he finds her, after which they share a tender interlude. Then, just two weeks later, their brief encounter ends as they are fated to part.

Plus, there are thrilling, life-or-death confrontations in the series. Three-ton elephant seals brawl over females. A pack of 25 wolves brings down a huge bison. A wide-eyed Weddell seal falls prey to hungry orca whales that, working as a team, can stir up giant waves to wash these frantic seals from the refuge of their ice floes.

And talk about "special effects"! An unprecedented time-lapse shot underwater records the growth of a brinicle -- an ice stalactite progressing downward toward the seabed -- killing everything its frozen plume touches. This otherworldly sight is as eerie and magical as a CGI effect from a sci-fi film. But it's real.

"That's the thing about the natural world: It gives you amazing natural drama," "Frozen Planet" series producer Vanessa Berlowitz says. "It looks like it's scripted, but we don't fake anything. Everything that we film is a complete portrayal of reality. And the audience thinks, 'Wow, they did that without trained animals!' "

Berlowitz has produced and directed a score of BBC documentaries, including two episodes of "Planet Earth," and, like Fothergill, she logged time at both poles for "Frozen Planet." She lived aboard a Royal Naval icebreaker for four months filming penguins and whales, and, in the Arctic, spent three weeks filming female polar bears and their cubs while she was five months' pregnant.

Through it all, the filmmakers served as passive observers. But they took a cinematic approach to planning multi-angle coverage of action they hoped would unfold.

"We were very keen to storyboard the sequences beforehand," Fothergill says. "Then, when we got on location, we would sit down and say, 'Have we got all the angles? Let's work it all out.'"

Adds Berlowitz, "We approached these holy-grail sequences thinking, 'What will it take?'"

The many up-close-and-personal scenes they bagged say as much about "Frozen Planet" as the vast scope of the enterprise, which can be expressed in remarkable statistics: four years in production; 38 camera people; combined number of days in the field: 2,356; 11/2 years at sea; hours trapped in blizzards: 840.

"The weather is often rubbish," Fothergill acknowledges. But physical discomfort isn't the real problem. "Everybody thinks it's all about storms and cold -- but it's actually about 'gray light,' when the ice looks really, really ugly. You can wait for weeks, and all the while the polar bear is doing his stuff, but you have to say, 'Don't shoot it. Wait until the light is good.' "

Today's episodes, "The Ends of the Earth" and "Spring," will be followed in subsequent weeks by "Summer" and "Winter." (Yes, the polar regions have seasons -- in fact, greater seasonal changes than anywhere else on our planet, as the series' narrator, Alec Baldwin, reminds us.)

On April 8, viewers go behind the cameras for a "Making Of" episode, which settles many how-did-they-get-that-shot questions raised by previous installments (and helps explain how people and equipment can function in temperatures as low as minus-58 degrees).

Then, as part of the two-hour finale on April 15, "On Thin Ice" investigates what climate change will mean for the people and wildlife at the poles, as well as the rest of the planet in between. This episode charting the effect of rising temperatures is reported by British naturalist David Attenborough (who hosted "Life in the Freezer" 19 years ago).

"The structure of our series," Fothergill says, "is to show the places. Then we engage in the animals' drama and lives. Then we show a bit of how we went about making the series. Then we let viewers learn about the environmental reality of it all in an objective, nonsensational, nonjudgmental way.'"

Hearing that, Berlowitz quotes the late ecologist-documentary superstar Jacques Cousteau, who famously noted, "We only protect what we love."

"Our goal," Berlowitz says, "is to do films that make people fall in love with the animals and places. What we want is for people to love them."

SOURCE :-http://www.southbendtribune.com/entertainment/inthebend/sbt-nature-makes-for-epic-star-in-frozen-planet-20120318,0,1661115.story

Tuesday, March 13, 2012

Miley Cyrus Talks Hunger Games: "The Hardest Part for Liam Was Being Away From Me!"

As if we weren't already dying of excitement for The Hunger Games premiere, our fave former-Disney darling Miley Cyrus was looking sex-ay as ever when she stepped out to support BF Liam Hemsworth.

And when Ashlan Gorse and Catt Sadler caught up with Miles on the charcoal and gold carpet at L.A. Live, they asked her what she thought the hardest part of filming H.G. was. To which she said, "I think the hardest part for Liam was being away from me."

Awww! She continues:


BUY Hunger games Earrings







"And his brother and his family," Miley—who donned a gorgeous glittery bustier and long black skirt by Pucci—explained. "At least he's not in a tour bus and is in a nice hotel somewhere. It's a little less bumpy, a little more sleep."

Liam seemed happy enough about his Hunger shoot though:

"On one hand, it's hard being on your own, but on the other, I'm making movies and it's something I love," Liam (who gushed about how "stunning" his girlfriend looked) said. "One of the great things about this job is traveling getting to see the country and the world."

And Miley was more than happy to keep chitchatting about her man, especially when it comes to their alone time together and fending off those pesky paparazzi:

"We have three dogs, so that takes up most of our time," Miley told us about what the twosome do during their downtime. "The only time we leave the house is to go to the pet store or the park...The paparazzi the other day, I told him to get a real job and he said ‘Yeah, you too!' and it's kind of true."

So how does she react to photogs like that?

"I thought he was kind of quick," Miley (who said she feels most comfortable spending time on the "chill" East Coast and in Nashville) laughed. "I said ‘You can have the picture, that's funny.'"

Unfortunately, the media attention won't be dying down anytime soon. Now that Liam is a huge franchise star, after all.

"I'm probably going to see this about 13 times," Miley said about seeing Hunger Games for the first time tonight. "I'm going to be a fan soon after this comes out. I'm going to be addicted."

Trust us, Miles, you're not the only one.

SOURCE : - http://uk.eonline.com/news/the_awful_truth/miley_cyrus_talks_hunger_games_the/300609



Friday, February 24, 2012

weight-loss drug Qnexa Drug approved by FDA

In a reversal, an FDA advisory committee backs the weight-loss drug Qnexa despite health risks after its maker, Vivus, promises strict oversight

A panel of medical experts voted overwhelmingly Wednesday to endorse the controversial weight-loss drug Qnexa, clearing the way for the Food and Drug Administration to approve a new prescription obesity medication for the first time since 1999.

The FDA will issue a final ruling later this year, but the agency typically follows the recommendations of its advisory committees.

The 20-2 vote in favor of Qnexa was a surprising reversal from 2010, when the same advisory committee decided that the drug's risks of heart problems and birth defects outweighed its weight-loss benefits.

In a clinical trial involving 4,323 people, Qnexa — a combination of the anticonvulsant drug topiramate and the appetite suppressant phentermine — led to an average loss of about 10% of total body weight in the first year of use. Many users also saw improvements in blood pressure.

But the trials also found that that the drug caused a slight increase in heart rate, which can boost the odds of a heart attack or stroke. In addition, researchers detected an increased risk of birth defects — typically cleft lip — in women who became pregnant while taking the drug.

Vivus Inc., the drug's manufacturer, addressed those concerns by proposing a tightly controlled system for prescribing Qnexa. To prevent birth defects, patients who take the drug will have to undergo monthly pregnancy testing and healthcare providers will get special training on the medication's risks and benefits. Vivus will also restrict distribution of the drug to registered pharmacies, among other measures.

"We will know who the prescribers are. We will know who has been trained," Dr. Barbara Troupin, Vivus' senior director of global medical affairs, told the advisory committee. "We are confident the Qnexa [risk management program] balances the safeguards while allowing access for appropriate patients."

According to the clinical trial data and previous studies, the risk of having a baby with a cleft lip is two to five times greater in women who took topiramate.

"The simple reality is, if you're pregnant or planning on getting pregnant, it's not the right drug for you," said Joe Nadglowski, chief executive of the Obesity Action Coalition, a patient advocacy group based in Tampa, Fla., that supports approval of Qnexa.

Vivus, based in Mountain View, Calif., proposed a similar program to monitor heart risks in patients. Several panel members strongly encouraged the company to conduct a post-marketing study to help identify the potential cardiovascular risks.

At the panel's daylong meeting Wednesday in Silver Spring, Md., several members of the Endocrinologic and Metabolic Drugs Advisory Committee said they worried about Qnexa's side effects but believed the benefits outweighed the risks.

More than 35% of American adults are obese, including about 5% who are morbidly obese, and an additional 33% are overweight, according to the Centers for Disease Control and Prevention in Atlanta. Those extra pounds are more than just a cosmetic issue; they also increase one's risk of diabetes, heart disease, stroke, osteoarthritis, certain types of cancers and possibly dementia.

"The most encouraging thing is that just about every member really heard the message about the need to treat obesity," said Ted Kyle, the advocacy committee chairman of the Obesity Society. "Obesity is not a trivial disease."

Only one prescription diet drug is available in the United States. That drug, orlistat, blocks absorption of fat and is sold under the trade name Xenical. Qnexa appears to work by suppressing appetite and increasing feelings of fullness.

It's not clear why the medication raises heart rate, but such an increase is typically viewed as a marker of cardiovascular risk, said Dr. Michael S. Lauer, director of the division of cardiovascular sciences at the National Heart, Lung and Blood Institute and a member of the advisory panel.

Lauer cast one of the two votes against approval, saying that the FDA should first ask Vivus to complete a study that provided detailed cardiovascular risk data. Otherwise, he said, FDA approval "would be a decision based on hopes, surrogates and suppositions."

"We have seen many cases in medicine where we thought we understood the pathology of disease … and we turned out to be wrong," Lauer said. "With an epidemic as serious as obesity, we need to do this right."

If approved by the FDA, Qnexa would be targeted for people with a body mass index of 30 or above, or a BMI of 27 or above for people who also have weight-related health problems, such as diabetes or sleep apnea. A BMI of 25 to 29 indicates a person is overweight, and 30 or greater is considered obese.

The vote sent Vivus shares soaring to more than $21 in after-hours trading, double the official closing price of $10.55.

Monday, February 20, 2012

Lent defination and Lent 2012 shedule

What is Lent?

Lent is a Christian Festival. In the past it was a long, strict religious fast when people gave up all rich food. The day before Lent starts is known as Shrove Tuesday.
Lent is the time when Christians prepare for the greatest of the Christian festivals known as Easter, by thinking of things they have done wrong.

It was a time for spring-cleaning lives, as well as homes.

What happens during Lent today?

The Christian church no longer imposes a strict fast. Lent is a time when some Christians try to overcome their own faults because they believe that it was man's sin which led Jesus to be crucified.

Some Christians try to follow the example of Jesus in the desert by giving up luxuries and practising self-discipline. And they try to put aside more time to prayer and religious acts so that they can really let God into their lives.

Bible Study
Many churches hold special Lent services. In some towns the churches of different denominations join together in groups to discuss and share their Christian faith.

When does Lent begin?

Lent begins with Ash Wednesday and lasts for six and a half weeks.

Lent is a moveable feast which means the date changes from year to year. We explain more on our Easter main page.
In 2012 Ash Wednesday is on 22 February

2009 — 25 February
2010 — 17 February
2011 — 9 March
2012 — 22 February
2013 — 13 February
2014 — 5 March
2015 — 18 February
2016 — 10 February
2017 — 01 March
2018 — 14 February
2019 — 06 March
2020 — 26 February
2021 — 17 February
2022 — 02 March

When does Lent end? When is Lent over?

Lent ends at Easter when Christians remember the execution of Jesus and then celebrate his rising from death.

The last week of Lent begins with Palm Sunday, which celebrates the day Jesus entered Jerusalem and the people lay down palms at his feet. The last day of Lent is Holy Saturday, the day before Easter Sunday (Easter Day)copyright of projectbritain.com

In the Roman Catholic Church, Lent officially ends at sundown on Holy Thursday (Maundy Thursday), with the beginning of the mass of the Lord's Supper.
The period of forty fast days and Sundays before Easter are known as Lent.

image: 2010 calendar showing 40 days
Calendar 2010

Why are Sundays not counted in the 40 days?

Sundays are always a day of celebration in the Christian church and so they cannot be included in the 40 fast days of Lent. Sundays commemorate the Resurrection. c

Why does Lent last for 40 days?

Lent is a time when Christians remember the 40 days and nights Jesus spent alone in the desert without food being tempted by the Devil. Jesus used this time to prepare for His work by fasting and praying.

Luke's Gospel says:

'Jesus, full of the Holy Spirit, returned from the Jordan and was led by the Spirit in the desert, where for forty days he was tempted by the devil. He ate nothing during those days, and at the end of them he was hungry.'

So, as in the Bible, Christians spend forty days in preparing themselves to rejoice at the resurrection of Jesus Christ at Easter.

Interesting fact

The number 40 is a special number in the Bible. It signifies preparation for something special:

* The rain lasted for 40 days in the mighty flood - Noah
* Moses stayed on the Mount Sinai forty days (Ex 24:18)
* Jonah gave the people of Ninevah forty days to repent (Jon 3:4)
* Jesus, before starting his ministry, spent forty days in the desert in prayer and fasting (Matt 4:2)

Source :http://www.woodlands-junior.kent.sch.uk/customs/lent.html